Streptomycin

Streptomycin is an antibiotic commonly known for being the first medical solution against tuberculosis. This was the first aminoglycoside molecule, consisting of amino-modified sugars, to be discovered (October 19, 1943 by Albert Schatz). This bactericide acts as a protein synthesis’ inhibitor; it binds to the ribosome of bacteria interfering with the binding of formyl-methionyl-tRNA. This phenomenon will directly affect the reading of codons, which will lead to inhibition of protein formation and, as consequence, the death of the bacteria.