Ty elements
comprise a family of dispersed repetitive DNA sequences that are found at
different sites in different strains of yeast. Ty is an abbreviation
for "transposon yeast", it has several features that are unique, and
it appears to resemble a primitive retrovirus and it can be found in Saccharomyces
cerevisiae . A
transposition event creates a characteristic footprint: 5 bp of target DNA are
repeated on either side of the inserted Ty element.
Recombination
between Ty elements seems to occur in bursts; when one event is
detected, there is an increased probability of finding others. Gene conversion
occurs between Ty elements at different locations, with the result
that one element is "replaced" by the sequence of the other.
Ty elements
terminate in short direct repeats and are transcribed into two overlapping
RNAs. They have two reading frames, with sequences related to the retroviral
gag and pol genes.
Only some of
the Ty elements in any yeast genome are active: most have lost the
ability to transpose (and are analogous to inert endogenous proviruses) and transposon yeast elements can
generate virus-like particles.
Group G1.1 Ana Abreu, Ana Martins, Daniela Garcia, Marta Rocha and Rita Natividade
Ref: Ndsu.edu,.
(2015). Transposable Genetic Elements. Retrieved 27 October 2015, from
https://www.ndsu.edu/pubweb/~mcclean/plsc431/transelem/trans2.htm
Boeke, J. D. et al. (1985). Ty elements transpose through an
RNA intermediate. From http://webcache.googleusercontent.com/search?q=cache%3Ahttp%3A%2F%2Fgenes.atspace.org%2F16.4.html&gws_rd=cr&ei=4SkuVqyYCoWbU6S6jvgB
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