Monday, December 3, 2012

γ-complex


For E. coli, γ-complex is a component from the enzyme DNA polymerase III, made up of five subunits and is known by interacting with the β subunit (sliding clamp).
It’s necessary for the regulation of the attachment and removal of the DNA polymerase III from the DNA template. This function is essential for the process of attachment and detachment of the enzyme during lagging strand replication, requiring ATP. This phenomenon occurs continuously from the beginning to the end of the Okazaki fragments.

DNA Polymerase III - γ-complex

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