Chromosome 2 (Saccharomyces cerevisiae)

Chromosome 2 (Saccharomyces cerevisiae)

    The DNA sequence of the yeast Saccharomyces cerevisiae chromosome II has 807 188 bp, whole the left arm has 238207 bp and the right arm has 575579 bp.  At present, it is the largest eukaryotic chromosome entirely sequenced.  This chromosome contains a total of 410 functional genes (covering 72% of the sequence). Searches revealed that 124 ORFs (30%) correspond to genes of known function, 51 ORFs (12.5%) appear to be homologues of genes whose functions are known, 52 others (12.5%) have the functions of which are not well defined and another 33 of the novel putative genes (8%).

This chromosome presents 21 ARS, such as: ARS201; ARS230; ARS202; ARS203; ARS206; of which the ARS203 (figure 1) is involved in replication.

In summary, Chromosome II has various genes that are responsible for very different functions, as you can see in the next link: https://wiki.yeastgenome.org/images/c/c4/Chr2.pdf

Figure 1- Sequence of the ARS203.

Grupo 1.2

Beatriz Ferreira

Diana Alves

Filipe Guimarães

Francisca Gonçalves

Samuel Rocha

2º ano Licenciatura em Bioquímica | Universidade do Minho