Tuesday, October 30, 2018

Saccharomyces Cerevisiae Chromosome IV




Saccharomyces cerevisiae Chromosome IV
The Saccharomyces cerevisiae chromosome IV is the longest of them all containing 1,531,974 base pairs and around 796 predicted and knowned genes having a lenght of 1531933bp (without the centromere).
Arms lenght:
·      Left arm- 449711bp
·      Right arm- 1082112bp
The average combination of G+C is 37.9% being lower than chromossome III (38.5%) and II (38.3%).
At the centromere (coordinates 500,000 to 1,215,000) there is a lower amount of G+C (37.4%) than the periferic regions (38.2%).
There are exactly 35 ARS (autonomously replicating sequences), apart from the total we take has an example ARS442. It’s sequence is the following:





From the genes involved in replication of the fourth chromosome we give special attention:
·      PSF1 / YDR013W
·      SLD5 / YDR489W
·      FOB1 / YDR110W
·      RAD30 / YDR419W
·      RAD55 / YDR076W

Cristiano Viães A84165 
Diogo Cachetas A83854 
Diogo Pinto A85142 
Sérgio Mendes A83835

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