Saccharomyces cerevisiae Chromosome VIII

The genome of Saccharomyces cerevisiae is made up of 16 chromosomes. The data presented in this document is our research on the Chromosome VIII. Chromosome VIII has a total length of 562643 bp and 385 genes. The centromere of this chromosome (FIG.1) is located between the bases 105586 and 105703 bp and contains 118 bp. The left arm has 105586 bp, while the right arm has 457 057 bp.

FIG.1 - Representative scheme of the Chromosome VIII Centromere.

From a total of 385 genes present in this chromosome (FIG.2), 321 are functional (ORF- open reading frame), which corresponds to 83,4%. Other significant percentages correspond to long terminal repeat (6,2%) and ARS - autonomously replicating sequence - (4,2%), which corresponds to 16 ARS in total, for example, ARS815 (its sequence as shown in FIG.3). There are many genes involved in replication (TAB.1)   

FIG.2 – Feature Types for Chromosome VIII

 FIG 3 - Nucleotide sequence for ARS815.

TAB 1 – Some genes in CHR VIII used for DNA Replication

Grupo 3.1
Ana Sousa, Sara Castro, Ana Luísa, Bruna Novais, Carolina Gonçalves

Licenciatura: Bioquímica

UMinho

Reference: M. Johnston, et al., 1994, Science 265:2077-82