Yeast Chromosome III
The entire DNA sequence of
chromosome III of the yeast Saccharomyces
cerevisiae has been determined. According to Oliver et al., “this is the
first complete sequence analysis of an entire chromosome from any organism”.
Chromosome III is the third
smallest chromosome in S. cerevisiae, the
sequence is 316,620 kilobases long, the left arm contains 114,385 kilobases and
the right arm contains 202,119 kilobases. This sequence reveals 198 genes of
which 184 are open reading frames (ORF), 10 are tRNA genes and 4 are snoRNA genes. This chromosome contains 19 autonomously
replicating sequences (ARS), such as ARS310 (fig. 1), and several genes
involved in replication, for example RIM1, DCC1, MRC1, RDS1.
Nucleotide sequence of ARS310:
Figura 1- Nucleotide sequence of ARS310
Reference:
Oliver et al.,
1992, The complete DNA sequence of yeast
chromosome III, Nature, vol. 357: 38-46.
Grupo 1.3
Ana Filipa Alves
de Araújo A85195
Cristiana Filipa
Leite Oliveira A85237
Filipa Leal Silva
A84224
Inês Mesquita
Ferreira A85289
Licenciatura em Bioquímica
UMINHO
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